KMID : 1143920190230010034
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Annals of Hepato-Biliary-Pancreatic Surgery 2019 Volume.23 No. 1 p.34 ~ p.40
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Gangrenous cholecystitis in male patients:A study of prevalence and predictive risk factors
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Gomes Carlos Augusto
Soares Cleber Junior Di Saverio Salomone Sartelli Massimo De Souza Silva Poliana Graciele Orlandi Agnes Silva Heringer Thais Lacerda Gomes Felipe Couto Catena Fausto
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Abstract
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Backgrounds/Aims: The prevalence and risk factors of gangrenous cholecystitis in male are unknown.
Objective: To verify the prevalence and risk factors of gangrenous cholecystitis in males.
Methods: This cross-sectional study includes 95 patients (59.5¡¾17.1 years), with clinical and histopathological diagnosis, operated laparoscopically on 2012-2016. Eligibility was decided based on the variables of age; tachycardia (£¾100 bpm); leukocytosis (£¾10,000/mm©ø); Murphy¡¯s sign; gallbladder wall thickness (£¾4 mm); biochemical tests, morbidities (diabetes, alcoholism, smoking) and mortality. Multivariate regression, the chi-squared and Prevalent Chances Ratio (PCR) were used to define a few parameters.
Results: The prevalence of gangrenous cholecystitis in men older than 50 years was 29.3%. The risk factors for the disease were as follows: diabetes mellitus (p=0.006, RCP=4.191), leukocytosis (p=0.003), gallbladder thickness greater than 4 mm (p=0.035, RCP=3.818), which increased mortality [(p=0.04) (RCP=8.001)]. Murphy¡¯s sign showed a negative association (p=0.002, RCP=0.204). Values close to significance were observed in relation to gamma glutamyl transferase (p=0.083, RCP=3.125) and hospital stay (p=0.061, RCP=2.765).
Conclusions: Male gender, and age older than 50 years, were correlated with a high prevalence of necrosis, higher than that reported in females. The risk factors for developing necrosis are the same as those described for female patients.
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KEYWORD
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Abdominal infections, Abdominal surgery, Cholecystectomy, Complication, Laparoscopic surgery
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